解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The evolution of karyotypically stabilized short-lived (SL) and long-lived (LL) cytoraces in the laboratory have been established and validated through our previous lifespan studies. In the present investigation, we examined the possible reason(s) for the differential longevity among selected members of SL and LL cyto...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g11-049
更新日期:2011-10-01 00:00:00
abstract::The octamer-binding transcription factor 4 gene (Oct4) plays a critical role in maintaining pluripotency during early mammalian embryonic development and self-renewal of embryonic stem (ES) cells. In this study, we cloned the Oct4 cDNA and 2.8-kb regulatory region upstream of the start codon in Guanzhong dairy goat ( ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g11-047
更新日期:2011-10-01 00:00:00
abstract::Numerous quantitative trait loci (QTL) have been detected in Brassica species, but fine-mapping of major QTL has advanced slowly. The development of functional markers can overcome this barrier. We used publicly available PlantGDB-assembled unique transcripts (PUTs) from Brassica species to design 7836 functional simp...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g11-042
更新日期:2011-09-01 00:00:00
abstract::We sequenced the entire coding region of the mitochondrial genome of Heterodera glycines. The sequence obtained comprised 14.9 kb, with PCR evidence indicating that the entire genome comprised a single, circular molecule of approximately 21-22 kb. The genome is the most T-rich nematode mitochondrial genome reported to...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g11-024
更新日期:2011-07-01 00:00:00
abstract::Simple sequence repeats (SSRs) or microsatellites are very useful molecular markers, owing to their locus-specific codominant and multiallelic nature, high abundance in the genome, and high rates of transferability across species. The soybean aphid (Aphis glycines Matsumura) has become the most damaging insect pest of...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g11-002
更新日期:2011-05-01 00:00:00
abstract::Visual quality of field pea (Pisum sativum L.) is one of the most important determinants of the market value of the harvested crop. Seed coat color, seed shape, and seed dimpling are the major components of visual seed quality of field pea and are considered as important breeding objectives. The objectives of this res...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-117
更新日期:2011-04-01 00:00:00
abstract::Polyploidization is one of the major driving forces in plant evolution and is extremely relevant to speciation and diversity creation. Polyploidization leads to a myriad of genetic and epigenetic alterations that ultimately generate plants and species with increased genome plasticity. Polyploids are the result of the ...
journal_title:Genome
pub_type: 杂志文章,评审
doi:10.1139/G10-107
更新日期:2011-03-01 00:00:00
abstract::cis-Elements CArG bound by serum response factor (SRF) are presently being intensively studied, but little is known about the substitution pattern of functional CArG elements. Here, we have performed the first evolutionary analysis of CArGome in the human and mouse genome through bioinformatic methods and statistical ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G10-105
更新日期:2011-02-01 00:00:00
abstract::Understanding the medical, economic, and ecological importance of black flies relies on correct identification of species. However, traditional taxonomy of black flies is impeded by a high degree of morphological uniformity, especially the presence of cryptic biodiversity, historically recognized by details of chromos...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G10-100
更新日期:2011-01-01 00:00:00
abstract::Wild Thinopyrum grasses are important gene pools for forage and cereal crops. Knowledge of their chromosome organizations is pivotal for efficient utilization of this important gene pool in germplasm enhancement programs. Expressed sequence tags derived simple sequence repeat (EST-SSR) markers for Thinopyrum bessarabi...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G10-088
更新日期:2010-12-01 00:00:00
abstract::Oilseed rape (Brassica napus) is an allotetraploid species consisting of two genomes, derived from B. rapa (A genome) and B. oleracea (C genome). The presence of these two genomes makes single nucleotide polymorphism (SNP) marker identification and SNP analysis more challenging than in diploid species, as for a given ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G10-079
更新日期:2010-11-01 00:00:00
abstract::Peanut (Arachis hypogaea L.) is one of the most important oil crops in the world. However, biotechnological based improvement of peanut is far behind many other crops. It is critical and urgent to establish the biotechnological platform for peanut germplasm innovation. In this study, a peanut seed cDNA library was con...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-074
更新日期:2010-10-01 00:00:00
abstract::Fire blight is a devastating bacterial disease of rosaceous plants. Its damage to apple production is a major concern, since no existing control option has proven to be completely effective. Some commercial apple varieties, such as 'Florina' and 'Nova Easygro', exhibit a consistent level of resistance to fire blight. ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-047
更新日期:2010-09-01 00:00:00
abstract::Septoria speckled leaf blotch (SSLB), caused by Septoria passerinii, is one of the most important foliar diseases of barley (Hordeum vulgare L.) in North America. The primary problem caused by this disease is substantial yield loss. The objective of this study was to determine the chromosomal location of SSLB resistan...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-032
更新日期:2010-08-01 00:00:00
abstract::Powdery mildew (caused by Microsphaera diffusa Cooke & Peck) is a common disease of soybean in many soybean-growing regions of the world and under greenhouse conditions. The previously reported Rmd locus of soybean for resistance to powdery mildew was mapped on soybean molecular linkage group J (chromosome 16). We hav...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-015
更新日期:2010-05-01 00:00:00
abstract::In this study we sequenced and analysed the complete mitochondrial (mt) genome of the Chilean predatory mite Phytoseiulus persimilis Athias-Henriot (Chelicerata: Acari: Mesostigmata: Phytoseiidae: Amblyseiinae). The 16 199 bp genome (79.8% AT) contains the standard set of 13 protein-coding and 24 RNA genes. Compared w...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g10-004
更新日期:2010-04-01 00:00:00
abstract::Comparative mapping is an important component of map-based cloning in large-genome cereal species. We describe evidence of a segmental chromosomal duplication harbouring CONSTANS-like genes in barley that predates the divergence of the Oryzoideae (rice) and Pooideae (brachypodium, barley, wheat) clades, and discuss th...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-101
更新日期:2010-03-01 00:00:00
abstract::Thermosensitive genic male-sterile (TGMS) rice is widely used in hybrid rice production. Because of its specific temperature requirement, it can be used only in a narrow rice-growing zone in Asia. A newly discovered TGMS line, G20S, has an opposite phenotype compared with normal TGMS lines. G20S is completely sterile ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-092
更新日期:2010-02-01 00:00:00
abstract::Light-harvesting-like (LIL) proteins are low-molecular-mass membrane proteins related to the light-harvesting complexes, which form the dominant antenna system in most photosynthetic eukaryotes. To analyze the LIL protein family, we mined a number of publicly available databases to identify members of this family in a...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-081
更新日期:2010-01-01 00:00:00
abstract::The cryptic wheat-alien translocation T5DL.5DS-5MgS(0.95), with leaf rust and stripe rust resistance genes Lr57 and Yr40 transferred from Aegilops geniculata (UgMg) into common wheat, was further analyzed. Molecular genetic analysis using physically mapped ESTs showed that the alien segment in T5DL.5DS-5MgS(0.95) repr...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G09-076
更新日期:2009-12-01 00:00:00
abstract::The Mpv17l protein has two isoforms, M-LPL and M-LPS, which both regulate the production of reactive oxygen species (ROS) and protect against mitochondrial oxidative stress and apoptosis. M-LPL is ubiquitously expressed, while M-LPS is expressed mostly in the kidney of aged animals. We identified a variety of transcri...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-061
更新日期:2009-11-01 00:00:00
abstract::Differences in genome size and gene content are among the most important signatures of microbial adaptation and genome evolution. Here, we investigated the patterns of genome variation among 10 natural strains of the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti, using pulse field gel electrophoresis (PFG...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-060
更新日期:2009-10-01 00:00:00
abstract::Selection of wheat germplasm for a range of quality traits has been a challenging exercise because of the cost of testing, the variation within testing data, and a poor understanding of the underlying genetics. The objective of this study was to identify quantitative trait loci (QTLs) underlying quality traits in whea...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-045
更新日期:2009-08-01 00:00:00
abstract::Bruchids (Coleoptera: Bruchidae) can cause serious damage to mungbean and several other leguminous crops and there is a strong association between small seed size and bruchid resistance. In investigating the feasibility of breeding large-seeded cultivars with high levels of bruchid resistance, we studied the relations...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G09-031
更新日期:2009-07-01 00:00:00
abstract::To investigate the effect of signal molecules and their receptor-associated genes on rat liver regeneration (LR) at the transcriptional level, the associated genes were originally obtained by retrieving the databases and related scientific publications; their expression profiles in rat LR were then checked using the R...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-022
更新日期:2009-06-01 00:00:00
abstract::A Robertsonian polymorphism resulting in diploid chromosome number ranging from 59 to 61 and constant chromosome arm number (fundamental number = 104) was observed in the albino rainbow trout (Oncorhynchus mykiss (Walbaum)) from the yellow color strain. In one individual, 90 mitotic chromosomes and 156 chromosome arms...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g09-009
更新日期:2009-04-01 00:00:00
abstract::Cashew (Anacardium occidentale L.), introduced into India about 400 years ago, is distributed widely in the coastal regions as spontaneous populations as well as in cultivation. Despite the plant's commercial exploitation, little is known about its actual introduction and diversification. We attempted to construct the...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-119
更新日期:2009-03-01 00:00:00
abstract::Genetic diversity in 20 elite blackgram (Vigna mungo (L.) Hepper) genotypes was studied using microsatellite and AFLP markers. Thirty-six microsatellite markers from azuki bean (Vigna angularis (Willd.) Ohwi & Ohashi) were successfully amplified across the 20 blackgram genotypes and 33 microsatellite markers showed po...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g08-107
更新日期:2009-02-01 00:00:00
abstract::Knowledge of the inheritance of C-glycosyl flavone synthesis in maize (Zea mays L.) silk tissues has been acquired through detailed genetic studies involving primarily germplasm from the Corn Belt Dent race. To test the robustness of this genetic knowledge, we examined C-glycosyl flavone synthesis in a genetically dis...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-100
更新日期:2009-01-01 00:00:00
abstract::A reminder that another paper on the cetacean PRNP locus has been published before Kim et al.'s paper (2008. Genome, 51: 452-464) is presented along with a consideration of the related results. ...
journal_title:Genome
pub_type: 评论,杂志文章
doi:10.1139/G08-091
更新日期:2008-12-01 00:00:00
abstract::High soil boron (B) constitutes a major soil problem in many parts of the world, particularly in low-rainfall areas and land under irrigation. Low accumulation of B in the shoot or grain of cereal crops is correlated with the maintenance of biomass production and grain yield under high B conditions, suggesting that th...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-084
更新日期:2008-12-01 00:00:00
abstract::The first SSR-based genetic linkage map of Cucurbita moschata was created by integrating the maps of two F2 populations with one common parent developed from the crosses Waltham Butternut (WB) x Nigerian Local (NL) and ZHOU (a hull-less type) x WB. The integrated C. moschata map comprises 205 SSR markers and two morph...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-072
更新日期:2008-11-01 00:00:00
abstract::We previously demonstrated that allopolyploidization could induce phenotypic variations and genome changes in a newly synthesized allotetraploid in Cucumis. To explore the molecular involvement of epigenetic phenomena, we investigated cytosine methylation in Cucumis by using methylation-sensitive amplified polymorphis...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-063
更新日期:2008-10-01 00:00:00
abstract::To clarify the phylogenetic relationships of Carthamus species, we performed sequence analysis of the nuclear stearoyl acyl carrier protein desaturase (SACPD) gene and the chloroplast intergenic spacer region between leucine and phenylalanine tRNA genes (trnL-trnF IGS) in 13 taxa of Carthamus. The previous division of...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-059
更新日期:2008-09-01 00:00:00
abstract::The objectives of the present research were to determine the effects of water stress on seed-quality traits and to map QTLs controlling the studied traits under two different water treatments in a population of sunflower recombinant inbred lines (RILs). Two experiments were conducted in greenhouse and field conditions...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-038
更新日期:2008-08-01 00:00:00
abstract::A key breeding objective in oat (Avena sativa L.) is cultivars with high and low beta-glucan content. In a targeted strategy to develop PCR-based markers linked to published beta-glucan content quantitative trait loci (QTLs) regions, 15 random amplified polymorphic DNA (RAPD) fragments were cloned and their sequences ...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-026
更新日期:2008-06-01 00:00:00
abstract::A spontaneously mutated male-sterile material was found among the offspring of the indica restorer line Jinhuiyihao. To understand the status and function of the related gene and clone the gene, a near-isogenic line (NIL) of the male sterility was bred, and characterization of the mutant and gene mapping were performe...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-013
更新日期:2008-05-01 00:00:00
abstract::Mutability of the w4 flower color locus in soybean, Glycine max (L.) Merr., is conditioned by an allele designated w4-m. Germinal revertants recovered among self-pollinated progeny of mutable plants have been associated with the generation of necrotic root mutations, chlorophyll-deficiency mutations, and sterility mut...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/G08-001
更新日期:2008-04-01 00:00:00
abstract::Recent genome size estimates for Arctic amphipods have revealed the largest genomes known in the Crustacea. Here we provide additional data for 7 species of caridean shrimp collected from the Canadian Arctic and the Gulf of St. Lawrence. Genome sizes were estimated by flow cytometry and haploid C-values ranged from 8....
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g07-108
更新日期:2008-02-01 00:00:00
abstract::The spectrum of resistance to isolates of Leptosphaeria maculans and the map location of a new blackleg resistance gene found in the canola cultivar Brassica napus 'Surpass 400' are described. Two blackleg resistance genes, LepR1 and LepR2, from B. rapa subsp. sylvestris and introgressed in B. napus were identified pr...
journal_title:Genome
pub_type: 杂志文章
doi:10.1139/g07-103
更新日期:2008-01-01 00:00:00